http://www.efkoli.com/3/events/2011-08-20/
The big question is: Will there be a cleare regulatory path in place toapprove lower-cosg biogenerics? The answer could come by the end of this After a roughly $800 milliom economic stimulus package and an overhauled financiaol system bailout, Congress may have littler appetite for more spending in the form of an Obama administration universal health care plan, said Jim president and CEO of the Biotechnologu Industry Organization. Legislation around lower-cost biogenerics — also calles biosimilars or follow-on biologics could make a nifty he said.
But the trouble with regulation — like the making of copycatf biologicsthemselves — rests in the The process for making biologics is more complex and riskgy than for traditional pharmaceuticals. That leaves biosimilars with several technological, regulatory and effectiveness question marks. Biologicas bind to a living cell, often from a plant or animal, and typically are South San Francisco-based Genentech’s Avastin and Herceptin, for are monoclonal antibodies, a fusionb of tumor and mammal cells that continually produce antibodies that attacjone target.
Old-school drugs, on the othert hand, are a mixture of chemicapl ingredients in pill orcapsule It’s not a matter of if biosimilars hit the U.S. but how. “Merely reproducing (a biologic) shouldn’t give you much confidencer that you’re ending up with the same Genentech Chairman and CEO Art Levinsonn said atlast month’s Healthcare “The should just be very careful.” Genentech, Levinsom said, has “no resistance to a good policy.” But Genentecuh has lots to lose if generic versions of its drugss come on the market in the next two to threre years. Biotech drugs are often more For example, Avastin, Genentech’ s top-selling drug at $2.
7 billion in 2008 sales, costs $50,000 a while adding only a few monthxof life. That cost, industryy leaders say, is mainly due to a drug-developmeny process that typically requires upwards of 10 yearsand $1 That isn’t stopping companies from pursuing them. late last year said it is buildin Merck BioVentures to focuson biologics, and a follow-on biologicv from Israel-based generics powerhouswe in February 2008 was the first biosimilar to win European Union Biogenerics could ring up more than $34 billion in sales from 2013 through 2017, according to , whicnh manages pharmacy benefits for employers and health “Everybody’s jumping in,” said Bryan Lawlis, CEO of in San “Even if there’s price erosion of 20 to 30 percent, you only have to get 10 percenf of the market and you’ll make money on the Itero, launched last year to make follow-onn proteins, is backed with $21 million in Series A financingy led by and Panorama Capital.
The secret to succes s in biosimilars may rest inthe company’w approach to the market, said Iteri Chief Medical Officer Dr. Darlene “Generic companies that are making the shift to biosimilarss may try to approacb it with a strategy similatr to their small moleculegeneric strategy,” she said. “Our view is they won’t be It’s hard to appreciate the nuanceswof biotech.” Regardless, they all will have to wait for which considered a handfup of biosimilar bills last year, including one from Peninsula Rep.
Anna This year’s crop of bills, Greenwood said, must considef data exclusivity, the period during whichh a follow-on biologic maker cannot rely onthe originator’s clinical data for approval. Last year’s key biogenerix bills, like Eshoo’s bill, granted at leasrt 12 years of exclusivity. But Greenwood said California Rep. Henryt Waxman, who now leads the House Energy & wants a seven-year window that’s simila to that for small-molecule generics. “The thinking behinr that is the price goesdown sooner,” Greenwoof said.
“That’s all completely but if there aren’t more years, you won’t recover your and you won’t innovate.”
sábado, 29 de octubre de 2011
miércoles, 26 de octubre de 2011
Amerijet acquires interest in Nations Express - The Business Review (Albany):
plesciamipukoa1855.blogspot.com
Amerijet recently announced its acquisitiomn ofSRX Transcontinental, a Florida-based company specializing in grounde handling operations throughout Central Asia, and owner of , an Uzbekistab certificated airline. Florida-based Amerijet serves destinations throughoutthe America’s, Mexico, the Caribbean, Europe, Asia, and the Middlew East. Its primary hub is at , with 210,000-square-foof export and 100,000-square-foot imports air cargp handling facilities anda 50,000-square-foot ocean cargo
Amerijet recently announced its acquisitiomn ofSRX Transcontinental, a Florida-based company specializing in grounde handling operations throughout Central Asia, and owner of , an Uzbekistab certificated airline. Florida-based Amerijet serves destinations throughoutthe America’s, Mexico, the Caribbean, Europe, Asia, and the Middlew East. Its primary hub is at , with 210,000-square-foof export and 100,000-square-foot imports air cargp handling facilities anda 50,000-square-foot ocean cargo
lunes, 24 de octubre de 2011
Hear ye, hear ye, these new employers have jobs! - Boston Business Journal:
tatyanagepoji.blogspot.com
While the state’s unemployment rate was 5.9 percenrt in March, according to the Department ofWorkforce that’s still lower than that month’s national rate of 8.5 A number of large employers have movedc operations to Albuquerque, are expanding or plan to open facilities here in cominyg months. The most visible have been companies related to the renewable energyindustry (see related story this page), as well as , whicnh hired 300 for its new operation in , and , whichy is building a new customer servicer center in Rio Rancho and has temporary spaces up and running now.
Randall Davis, transition manager for HP, said the compan plans to hire up to 600 by the end of the year even beforr the new facilityis completed. HP plans to have 1,800 full-time employees in Rio Rancho over the next 15 yearse and an annual expected payrollof $54 Fidelity Investments has about 300 people working at its new buildinyg in Mesa del Sol, soutj of the . The company has said its long-term plansx call for increasing thatto 1,200. But Jennifetr Engle, spokeswoman for the declined to speculate on additional hiring atthis time. The compan is still filling some positions.
The film and media industry, lured by New Mexico’s tax incentives, continuea to grow here and attractnew companies. , whicu opened its new headquarters in Albuquerque recentlyat , has hiredx about 85 people here and move 15 more from its other sites. Theree are still some positions open in production and Web operationw as wellas programming. Productions are bringingg plenty of work for New Mexicofilm Recently, the International Alliance of Theatrical and Stage Employeex (IATSE) Local 480 and the state film office hostede seminars to help construction workersw learn how to transition to work on film productions.
Many crew jobs come throug IATSE, but there are multiple jobs in the industrythat don’y require going through the union, said Jon business agent for There are other unions, as well as resourcse lists for casting calls and other jobs (see linka in box). “We have literallgy hundreds of members who started as got to know theird way aroundthe set, go to know the production picked up days, and are now full-time working professionals,” Hendrh said.
Several retailers are also expanding inNew Mexico, despite the recession’ s impact on that Sunflower Farmers Market, based in Boulder, will open four stores in the next 18 months and hire 400 Three of the stores will be in Albuquerqure and one will be in Santa Fe. And anothed Colorado company, America’s is opening six franchise stores in Albuquerqu e and one inSanta Fe. The first storesx open this month. The company’s franchisee for this Patrick Unverferth, will hire 24 people to stafcfthe stores.
is hiring about 420 people to staff a new supercenterd opening this summer in northeast Government remains the top employer in New thanks in large part to the presence of the national military bases, federal agencies with substantial operationx here (including the , the Bureau of Indiann Affairs and the ) and private contractors who do work for the USAJobs.gov, the official job site of the U.S. government, listx more than 1,000 jobs in New Mexico, varyinh from human resource specialiststo physicians, biologists and vehiclwe maintenance workers. The 2010 Census is also hirin g inNew Mexico.
Tribal governments have also consistentlyadderd jobs, even during the economic according to monthly employment reports from the New Mexico Departmenyt of Workforce Solutions. Many of New Mexico’s tribal governments cannot fill all the available jobs with tribal members and employ people from outside their specific Many of these are in hotels andcasinose (see story on Tourism, page one), but not all of And although the statre of New Mexico implementedf a hiring freeze late last year, there are some jobs that have been exemptedx from that freeze.
Personal & Home Care Aides 6,190o Retail Sales workers 6,030 Combined Food Preparation Servers 5,400 Retail Salespersons 4,770 Customer Servicer Representatives 3,240 Cooks & Food Preparatioj workers 3,230 Home Health Aides 3,190 Registereds Nurses 2,920 Elementary School Teachers 2,53 0 Waiters & Waitresses 2,420 Correctional Officers & Jailera 2,180 Janitors & Cleaners 2,060 Officw Clerks, general 1,850 Bookkeeping, Accounting Auditing Clerks 1,620 Nursing Aides, Orderlies & Attendants 1,43o Maids & Housekeeping Cleaners 1,420 Middle School Teachers 1,310 Secondary Schoop Teachers 1,300 Construction Laborers 1,210 Restaurants 1,190 Maintenance & Repair workers 1,15p Accountants & Auditors 1,150 Receptionists Information Clerks 1,140 Executive Secretaries & Admin.
Assistants 1,120 Source: Departmenrt of Workforce Solutions, “New Mexico Employmenty Projections 2006-2016.” Full report available at: www.dws.state.nm.us/LMI/pdf/2016projections.pdf
While the state’s unemployment rate was 5.9 percenrt in March, according to the Department ofWorkforce that’s still lower than that month’s national rate of 8.5 A number of large employers have movedc operations to Albuquerque, are expanding or plan to open facilities here in cominyg months. The most visible have been companies related to the renewable energyindustry (see related story this page), as well as , whicnh hired 300 for its new operation in , and , whichy is building a new customer servicer center in Rio Rancho and has temporary spaces up and running now.
Randall Davis, transition manager for HP, said the compan plans to hire up to 600 by the end of the year even beforr the new facilityis completed. HP plans to have 1,800 full-time employees in Rio Rancho over the next 15 yearse and an annual expected payrollof $54 Fidelity Investments has about 300 people working at its new buildinyg in Mesa del Sol, soutj of the . The company has said its long-term plansx call for increasing thatto 1,200. But Jennifetr Engle, spokeswoman for the declined to speculate on additional hiring atthis time. The compan is still filling some positions.
The film and media industry, lured by New Mexico’s tax incentives, continuea to grow here and attractnew companies. , whicu opened its new headquarters in Albuquerque recentlyat , has hiredx about 85 people here and move 15 more from its other sites. Theree are still some positions open in production and Web operationw as wellas programming. Productions are bringingg plenty of work for New Mexicofilm Recently, the International Alliance of Theatrical and Stage Employeex (IATSE) Local 480 and the state film office hostede seminars to help construction workersw learn how to transition to work on film productions.
Many crew jobs come throug IATSE, but there are multiple jobs in the industrythat don’y require going through the union, said Jon business agent for There are other unions, as well as resourcse lists for casting calls and other jobs (see linka in box). “We have literallgy hundreds of members who started as got to know theird way aroundthe set, go to know the production picked up days, and are now full-time working professionals,” Hendrh said.
Several retailers are also expanding inNew Mexico, despite the recession’ s impact on that Sunflower Farmers Market, based in Boulder, will open four stores in the next 18 months and hire 400 Three of the stores will be in Albuquerqure and one will be in Santa Fe. And anothed Colorado company, America’s is opening six franchise stores in Albuquerqu e and one inSanta Fe. The first storesx open this month. The company’s franchisee for this Patrick Unverferth, will hire 24 people to stafcfthe stores.
is hiring about 420 people to staff a new supercenterd opening this summer in northeast Government remains the top employer in New thanks in large part to the presence of the national military bases, federal agencies with substantial operationx here (including the , the Bureau of Indiann Affairs and the ) and private contractors who do work for the USAJobs.gov, the official job site of the U.S. government, listx more than 1,000 jobs in New Mexico, varyinh from human resource specialiststo physicians, biologists and vehiclwe maintenance workers. The 2010 Census is also hirin g inNew Mexico.
Tribal governments have also consistentlyadderd jobs, even during the economic according to monthly employment reports from the New Mexico Departmenyt of Workforce Solutions. Many of New Mexico’s tribal governments cannot fill all the available jobs with tribal members and employ people from outside their specific Many of these are in hotels andcasinose (see story on Tourism, page one), but not all of And although the statre of New Mexico implementedf a hiring freeze late last year, there are some jobs that have been exemptedx from that freeze.
Personal & Home Care Aides 6,190o Retail Sales workers 6,030 Combined Food Preparation Servers 5,400 Retail Salespersons 4,770 Customer Servicer Representatives 3,240 Cooks & Food Preparatioj workers 3,230 Home Health Aides 3,190 Registereds Nurses 2,920 Elementary School Teachers 2,53 0 Waiters & Waitresses 2,420 Correctional Officers & Jailera 2,180 Janitors & Cleaners 2,060 Officw Clerks, general 1,850 Bookkeeping, Accounting Auditing Clerks 1,620 Nursing Aides, Orderlies & Attendants 1,43o Maids & Housekeeping Cleaners 1,420 Middle School Teachers 1,310 Secondary Schoop Teachers 1,300 Construction Laborers 1,210 Restaurants 1,190 Maintenance & Repair workers 1,15p Accountants & Auditors 1,150 Receptionists Information Clerks 1,140 Executive Secretaries & Admin.
Assistants 1,120 Source: Departmenrt of Workforce Solutions, “New Mexico Employmenty Projections 2006-2016.” Full report available at: www.dws.state.nm.us/LMI/pdf/2016projections.pdf
sábado, 22 de octubre de 2011
Missouri's useless exercise - Kansas City Star
ignatiywulyxura.blogspot.com
Missouri's useless exercise Kansas City Star 7 primary will be little more than a confusing exercise in good ol' Missouri futility. Instead, Republicans will pick their convention delegates through an old-fashioned caucus system a few weeks later that few voters will attend. ... |
jueves, 20 de octubre de 2011
P&G moving Iams headquarters to Mason - Dallas Business Journal:
modestofyeyko.blogspot.com
Kris Parlett, spokesman for Procter and Gamble PG) Pet Care, which includee Iams and Eukanuba, said the company and its 240 employeesz would be moving in October to the Masonbbusiness park, where other personal healtyh care divisions of P&G and more than 2,00p0 employees are housed. “Itf will make it easier to collaborate andincrease productivity,” Parletty said. Nobody will be laid of as a resulf ofthe company’s current headquartera On Poe Avenue closing. Instead, all 240 employees will be offere there same positionsin Mason. P&G acquire Iams in 1999. Since then, sales of its Iams and Eukanubq brands have more than according tothe company.
“Oud home address is changing but not our commitment to improvinvgthe well-being of all dogs and said Dan Rajczak, vice president of P&G’d pet care business in North America, in a statemenr released Thursday. “If anything, this will help us do an even bettee job of connecting with our colleagues in health care to bring great innovation topet care.” A company spokespersonj confirmed that 250 employeezs at the Iams-Eukanuba manufacturing and R&D complex in Preblw County will not be part of the The news of the move came as a surprisse to Vandalia officials Thursday, who said they had been working vigilantlu behind the scenes to keep Iams “When P&G purchased we knew at that poingt this was a possibility some said Rich Hopkins, director of communicationsw for the city.
“But we are surprised todau that the announcementwas made.” Hopkins said Iams was one of the top employeres in Vandalia, though he could not say how much income was generatexd by the company. The city will have a presx conference at3 p.m. Thursday to further discussz the implications ofthe Meanwhile, the community is still pursuing two projects, including an $81 millionn distribution center, which would bring 700 jobs and New-Yorki based aerospace company that could brinf 130 jobs.
“This is bad news for any community,” Hopkins “We have two projects in the pipelinwe now that could bring up to 900 employees to the so it’s not all gloom and doom
Kris Parlett, spokesman for Procter and Gamble PG) Pet Care, which includee Iams and Eukanuba, said the company and its 240 employeesz would be moving in October to the Masonbbusiness park, where other personal healtyh care divisions of P&G and more than 2,00p0 employees are housed. “Itf will make it easier to collaborate andincrease productivity,” Parletty said. Nobody will be laid of as a resulf ofthe company’s current headquartera On Poe Avenue closing. Instead, all 240 employees will be offere there same positionsin Mason. P&G acquire Iams in 1999. Since then, sales of its Iams and Eukanubq brands have more than according tothe company.
“Oud home address is changing but not our commitment to improvinvgthe well-being of all dogs and said Dan Rajczak, vice president of P&G’d pet care business in North America, in a statemenr released Thursday. “If anything, this will help us do an even bettee job of connecting with our colleagues in health care to bring great innovation topet care.” A company spokespersonj confirmed that 250 employeezs at the Iams-Eukanuba manufacturing and R&D complex in Preblw County will not be part of the The news of the move came as a surprisse to Vandalia officials Thursday, who said they had been working vigilantlu behind the scenes to keep Iams “When P&G purchased we knew at that poingt this was a possibility some said Rich Hopkins, director of communicationsw for the city.
“But we are surprised todau that the announcementwas made.” Hopkins said Iams was one of the top employeres in Vandalia, though he could not say how much income was generatexd by the company. The city will have a presx conference at3 p.m. Thursday to further discussz the implications ofthe Meanwhile, the community is still pursuing two projects, including an $81 millionn distribution center, which would bring 700 jobs and New-Yorki based aerospace company that could brinf 130 jobs.
“This is bad news for any community,” Hopkins “We have two projects in the pipelinwe now that could bring up to 900 employees to the so it’s not all gloom and doom
martes, 18 de octubre de 2011
Ethel Burton - People's Tribune
vilyfijohy.wordpress.com
Ethel Burton People's Tribune You can leave a response or trackback to this entry Ethel Burton, 87, of Silex, died Wednesday, Oct. 12, 2011 at Silex Community Care. Private services to be held at a later date. Memorials may be made to donor's choice, c/o the McCoy-Blossom Funeral ... |
domingo, 16 de octubre de 2011
Republic Airways will buy Midwest Airlines - Atlanta Business Chronicle:
iwyqaxewun.wordpress.com
Milwaukee-based Midwest has a hub at , and Denver-basede Frontier flew about 10 flights out of KCI before it filefd for bankruptcy inApril 2008. Midwest had a 6.4 percent market share at KCI inApripl — the most recent month for which the has data and Frontier had a 3.1 percent markeft share. Frontier occupies two gates in KCI’ss Terminal C, and Midwest occupiees three gates inTerminal A. RJET) will buy all the equity in Midwesyfrom , a Fort Worth, Texas, private equityt firm. Republic also will buy TPG’s $31 millioj secured note from Midwest.
Consideration will be $6 milliobn in cash and a $25 million, five-year note, whichg may be converted to Republic stockat $10 a In addition, TPG will have the righft to nominate a member to the Republic The transaction is subject to customaryy regulatory approvals and is expected to close in four to six “The question is (about) the intentionn of Republic and what they plan to do if they end up ownin both these carriers,” Justin manager of air service development for the Kansas City Aviation said in a Wednesday interview. “This is (Republic’s) first foray into operations onthis scale, where they actuall own the airline.
I woule assume Republic will continue doing what Midwest and Frontie r havebeen doing, but it could make sense at some pointt to make changes for economy of Republic uses an airplanse model that’s “the right size plane for this Meyer said. “This is really a bold move by he said. “Everybody’s saying it’s a buyer’a market right now.” Republic operates , Republic Airlines and . Those airlines offer scheduled passenger service onabout 1,200 flights daily to 101 cities in 37 states, Canada and Mexico through airline services agreements with seven U.S. including Midwest.
Midwest will become a wholly owned subsidiary and will continue to operate as abrandedd carrier. Rick Schifter, a partnee with TPG Capital, said the transaction secureds a more certain futurefor Midwest. “At the time we acquirexd Midwest, we envisioned that it would ultimately become part of a largefr airlineand network, as the abilitt to operate as a small, independenyt carrier is increasingly challenging in this economic he said. On Monday, Republic said it reached an investment agreement with bankrupt Frontier Airlines that will result in Frontier becomingb a wholly owned subsidiary of Republic for a priceof $108.75 million.
Republic has been one of thre e companiesfinancing Frontier’s emergence from bankruptcy. Republic Airlines also is oneof Frontier’ws major unsecured creditors, having filed a $260 millioh damage claim for Frontier’s breaking an agreement with Republic to operate regional jet service after Frontier file for bankruptcy protection.
Milwaukee-based Midwest has a hub at , and Denver-basede Frontier flew about 10 flights out of KCI before it filefd for bankruptcy inApril 2008. Midwest had a 6.4 percent market share at KCI inApripl — the most recent month for which the has data and Frontier had a 3.1 percent markeft share. Frontier occupies two gates in KCI’ss Terminal C, and Midwest occupiees three gates inTerminal A. RJET) will buy all the equity in Midwesyfrom , a Fort Worth, Texas, private equityt firm. Republic also will buy TPG’s $31 millioj secured note from Midwest.
Consideration will be $6 milliobn in cash and a $25 million, five-year note, whichg may be converted to Republic stockat $10 a In addition, TPG will have the righft to nominate a member to the Republic The transaction is subject to customaryy regulatory approvals and is expected to close in four to six “The question is (about) the intentionn of Republic and what they plan to do if they end up ownin both these carriers,” Justin manager of air service development for the Kansas City Aviation said in a Wednesday interview. “This is (Republic’s) first foray into operations onthis scale, where they actuall own the airline.
I woule assume Republic will continue doing what Midwest and Frontie r havebeen doing, but it could make sense at some pointt to make changes for economy of Republic uses an airplanse model that’s “the right size plane for this Meyer said. “This is really a bold move by he said. “Everybody’s saying it’s a buyer’a market right now.” Republic operates , Republic Airlines and . Those airlines offer scheduled passenger service onabout 1,200 flights daily to 101 cities in 37 states, Canada and Mexico through airline services agreements with seven U.S. including Midwest.
Midwest will become a wholly owned subsidiary and will continue to operate as abrandedd carrier. Rick Schifter, a partnee with TPG Capital, said the transaction secureds a more certain futurefor Midwest. “At the time we acquirexd Midwest, we envisioned that it would ultimately become part of a largefr airlineand network, as the abilitt to operate as a small, independenyt carrier is increasingly challenging in this economic he said. On Monday, Republic said it reached an investment agreement with bankrupt Frontier Airlines that will result in Frontier becomingb a wholly owned subsidiary of Republic for a priceof $108.75 million.
Republic has been one of thre e companiesfinancing Frontier’s emergence from bankruptcy. Republic Airlines also is oneof Frontier’ws major unsecured creditors, having filed a $260 millioh damage claim for Frontier’s breaking an agreement with Republic to operate regional jet service after Frontier file for bankruptcy protection.
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